A neighbor hunting buddy recently asked me if he could give penicillin orally? I told him that the label states that it should be administered inter-muscularly (IM). I do inject penicillin under the loose skin of the neck area sometimes. Someone on here recently posted that he gives Tylan 200 orally when his hounds has the kennel cough. It would seem to me that the digestive action of the stomach, intestines, and colon would somehow destroy the medicinal effect of the antibiotic. This is a topic that needs addressing. Dr. Chip or Lora, would you venture an opinion on this subject. Of course, anyone else's thinking is welcomed too as I would like to know. Good Time Charlie from southern Illinois.